Targets, assays, animal models, and early safety/tox studies before human trials.
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Wistar Institute researchers found that the neurotransmitter neuromedin U suppresses T cell infiltration at the earliest stage of neuroendocrine prostate cancer, and blocking it restored sensitivity to immunotherapy in experimental models.
There could be between two and seven million people experiencing venomous snake bites each year, scientists say The incidence of snake bites and related deaths is much higher than previously estimated, according to a major global study that calls for…
A new study reveals snake envenoming is a far greater public health crisis than previously understood, with sub-Saharan Africa bearing the heaviest toll. Researchers used geostatistical modeling to estimate up to 7 million envenomings and over 500,000 deaths annually, highlighting the urgent…
Intel Accelerates Open Infrastructure for the Agentic AI Era The additional analyses showed broader clinical responses versus placebo, alongside higher rates of serious heart failure events. At 36 weeks, aficamten improved a composite exercise score versus placebo (p The update broadens…
WAUWATOSA — Gov. Tony Evers and Milwaukee County Executive David Crowley joined local leaders Friday to celebrate the opening of a new forensic science and protective medicine facility. The four-story facility houses Wisconsin’s Milwaukee Crime Lab, the Milwaukee County Medical Examiner’s…
OnVagus has received approval to begin the first human trial of its noninvasive vagus nerve-stimulation device for cancer-related wasting at MD Anderson Cancer Center.
Deleting the Ssu72 phosphatase specifically in B cells sharply reduces IgE and IgG1 production and lung inflammation in a mouse model of allergic asthma, revealing a novel intracellular regulator of allergic antibody responses. Subject of Research: The role of the B cell-intrinsic…
CMEPlanet PRLog 2026 AHA CME Symposium - Inflammation as a Therapeutic Target in ASCVD - Describe the role of the IL-1βgIL-6gCRP inflammatory pathway in atherosclerotic plaque progression and rupture, and explain the clinical evidence supporting hsCRP as an independent predictor of recurrent MACE in…
Peng Gao, assistant professor of environmental health and exposomics at Harvard T.H. Chan School of Public Health, was awarded an NIH Director’s New Innovator Award from the National Institutes of Health’s High-Risk, High-Reward Research program. The award was one of 57 new…
Credit: UL Research Institutes UL Research Institutes’ Chemical Insights’ scientists will share their latest information on chemical and exposure safety at the 2026 International Society of Exposure Science (ISES) Annual Meeting in Vancouver, Canada. Chemical Insights is hosting a symposium, five…