Microbiology & Virology

Bacteria, viruses, microbiomes, and the invisible engines of life.

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Silent Genes of an Antarctic Fungus Wake Up to Reveal Hidden Chemistry

The first annotated genome of the Antarctic fungus Pseudogymnoascus australis reveals 44 biosynthetic gene clusters, most of them novel, and chemical elicitation successfully activates previously silent metabolic pathways. Subject of Research: Genome mining and elicitation of silent biosynthetic pathways in the…